Optimisation of warfarin-dosing algorithms for Han Chinese patients with CYP2C9*13 variants

ConclusionOur study showed that the algorithm-predicted doses should be lowered forCYP2C9*13 carriers. Inclusion of theCYP2C9*13 variant in the warfarin-dosing algorithm tends to predict the warfarin maintenance dose more accurately and improves the efficacy and safety of warfarin administration in Han Chinese patients.

http://link.springer.com/10.1007/s00228-023-03540-1

Source: European Journal of Clinical Pharmacology - July 17, 2023 Category: Drugs & Pharmacology Source Type: research