Viruses, Vol. 15, Pages 1544: Atypical Hepatitis B Virus Serology Profile & mdash;Hepatitis B Surface Antigen-Positive/Hepatitis B Core Antibody-Negative & mdash;In Hepatitis B Virus/HIV Coinfected Individuals in Botswana

Conclusions: We report a high HBsAg+/anti-HBc- atypical serology profile prevalence among PWH in Botswana. We caution against HBV-testing algorithms that consider only anti-HBc+ samples for HBsAg testing, as they are likely to underestimate HBV prevalence. Studies to elucidate the mechanisms and implications of this profile are warranted.

Source: Viruses - July 13, 2023 Category: Virology Authors: Bonolo B. Phinius Motswedi Anderson Margaret Mokomane Irene Gobe Wonderful T. Choga Tsholofelo Ratsoma Basetsana Phakedi Gorata Mpebe Doreen Ditshwanelo Rosemary Musonda Joseph Makhema Sikhulile Moyo Simani Gaseitsiwe Tags: Brief Report Source Type: research