Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial - Jones CMP, Day RO, Koes BW, Latimer J, Maher CG, McLachlan AJ, Billot L, Shan S, Lin CWC, McLachlan H, Webb M, Hamilton M, Ahedi H, Barber A, Mak W, Mathieson S, Petrova V, Bompoint S, Shan S, Murnion B, Buckley N, Demirkol A, Wrigley P, Needs C, Brooks L, Cantori S, Preisz P, Aitken J, Allan S, Burke M, Cameron G, Cepeda FJV, Davis C, Dullur J, Emmanuel J, Errey C, Fieuw-Makaroff S, Gaudry A, Genua L, Longhurst I, McCroary K, Merhi D, Nguyen T, Obayd ZR, Penm M, Pobbathi S, Poh WS, Schnitzler P, Shahnaz S, Tan V, Tang D, Tan B, Thu WK, Triantopolous T, Venkatesan R, Wong WCF, Yang SC.

Background Opioid analgesics are commonly used for acute low back pain and neck pain, but supporting efficacy data are scarce. We aimed to investigate the efficacy and safety of a judicious short course of an opioid analgesic for acute low back pain and n...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news