Impact of body mass index and its change on survival outcomes in patients with early breast cancer: A pooled analysis of individual-level data from BCIRG-001 and BCIRG-005 trials

CONCLUSIONS: In early breast cancer patients treated with adjuvant chemotherapy, baseline severe obesity was significantly linked to worse DFS and OS, and a BMI loss over 10% from baseline to post-adjuvant chemotherapy also negatively affected OS. Moreover, the prognostic role of BMI might differ between docetaxel-based and non-docetaxel-based groups.PMID:37429049 | DOI:10.1016/j.breast.2023.07.002

Source: Breast - July 10, 2023 Category: Cancer & Oncology Authors: Haizhu Chen Xiaoyan Qian Yunxia Tao Daquan Wang Ying Wang Yunfang Yu Herui Yao Source Type: research