Therapeutic effects against high-grade glioblastoma mediated by engineered induced neural stem cells combined with GD2-specific CAR-NK

ConclusionsPBMC-derived iNSCsTK showed a significant tumor-tropic migration and an effective anti-tumor activity with GCVin vitro andin vivo. In addition, combined with GD2NK92, iNSCsTK therapeutic efficacy improved dramatically to prolong the tumor-bearing animal model's median survival.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research