Reparative dentin formation following dental pulp capping is mediated by TNFR1 in vivo

TNF- α is a pro-inflammatory cytokine that promotes biomineralization in vitro in dental pulp cells. However, the role of TNF-α-TNFR1 signaling in reparative dentin formation and related inflammatory pathways is not known. Therefore, the aim of this study was to evaluate the role of the TNF-α-TNFR1 ax is in dental pulp repair following pulp capping in vivo.

Source: Journal of Endodontics - July 7, 2023 Category: Dentistry Authors: Luciano Aparecido de Almeida-Junior, Lisa Danielly Curcino Araujo, Giuliana Campos Chaves Lamarque, Maya Fernanda Manfrin Arnez, Yvonne Lorraine Kapila, L éa Assed Bezerra da Silva, Francisco Wanderley Garcia de Paula-Silva Tags: Basic Research-Biology Source Type: research