Issue Information

Front coverThe life cycle of a protein encompasses its synthesis by the ribosome, chaperone-assisted folding, posttranslational modifications, subcellular localization and, finally, protein turnover. Knowledge on the complexity of mechanisms driving protein homeostasis, or proteostasis, has grown considerably over the past decades, as well as the appreciation of the importance of proteostasis to brain functions, including cognition, mood, sleep, and appetite. Understanding the intricate mechanisms that act to preserve proteostasis may, therefore, result in novel treatments for neurodevelopmental and neurodegenerative disorders. This special issue on “Brain Proteostasis in Health and Disease”, edited by Mychael Lourenco, features both original work and review articles on key findings and recent advances in the field.Read the full article‘EDITOR SPOTLIGHT: Interview with Brain Proteostasis Special Issue Guest Editor Mychael Lourenco’ by JNC Editorial Office, K. H. Kwan, and M. V. Lourenco (J. Neurochem. vol. 166 (1), pp. 7–9) on doi:10.1111/jnc.15888
Source: Journal of Neurochemistry - Category: Neuroscience Tags: ISSUE INFORMATION Source Type: research