Effect of hydroxyurea on erythrocyte apoptosis in hemoglobinopathy patients

CONCLUSION: Hydroxyurea reduces the expression of phosphatidylserine on erythrocytes, contributing to the beneficial effects of this therapy. We suggest that the use of such a biological marker in conjunction with HbF levels may provide valuable insights into the biology and consequences of early RBC apoptosis.PMID:37394969 | DOI:10.1080/17474086.2023.2231152

Source: Expert Review of Hematology - July 3, 2023 Category: Hematology Authors: Neha Kargutkar Anita Nadkarni Source Type: research