Not just snot: local inflammatory profiles in patients with aspirin ‐exacerbated respiratory disease differ from patients with aspirin‐tolerant chronic rhinosinusitis

Key PointsIL-5, CCL2, and CXCL8 in sinus mucous are higher in patients with AERD relative to aspirin-tolerant patients with CRSThese mediators are pleiotropic, leading to widescale inflammatory processes contributing to AERDAERD is not only a T2 disease but heterogeneous: this may explain the refractory nature of AERD

Source: International Forum of Allergy and Rhinology - July 5, 2023 Category: Allergy & Immunology Authors: Simon Chiang, Sophie E. Yu, Tejas S. Athni, Regan W. Bergmark, Alice Z. Maxfield, Rachel E. Roditi, Kathleen M. Buchheit, Marie Lundberg, Margaret B. Mitchell, Stella E. Lee Tags: RESEARCH NOTE Source Type: research