Glycolysis regulator PFKP induces human melanoma cell proliferation and tumor growth

ConclusionCollectively, these results indicate that PFKP expression in melanoma cells increases proliferation and glycolytic activity in vitro and promotes tumorigenesis in vivo, suggesting that suppression of PKFP and inhibition of glycolysis may potently suppress melanoma progression.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research