VarID2 quantifies gene expression noise dynamics and unveils functional heterogeneity of ageing hematopoietic stem cells

Variability of gene expression due to stochasticity of transcription or variation of extrinsic signals, termed biological noise, is a potential driving force of cellular differentiation. Utilizing single-cell ...

Source: Genome Biology - June 23, 2023 Category: Genetics & Stem Cells Authors: Reyna Edith Rosales-Alvarez, Jasmin Rettkowski, Josip Stefan Herman, Gabrijela Dumbovi ć, Nina Cabezas-Wallscheid and Dominic Grün Tags: Method Source Type: research