Perturbations in indices of oxidative stress, oxidative DNA damage and lung function in chronic exposure to wood dust in Southern Nigeria

CONCLUSION: The association of exposure to wood dust with elevated indices of inflammation, OS, lipid peroxidation, oxidative DNA damage, and reduction in antioxidants and peak expiratory flow rate; and the concomitant increase in oxidative DNA damage and inflammation with increasing duration of exposure suggest that these indices may be useful in predicting woodworkers at risk of development of chronic lung conditions.PMID:37326599 | DOI:10.1080/08958378.2023.2224388

Source: Inhalation Toxicology - June 16, 2023 Category: Respiratory Medicine Authors: Augusta Chinyere Nsonwu-Anyanwu Raymond Ekong Eworo Unyime Aniekpon Fabian Uduak Luke Caroline Chinenyenwa Thomas Olivia Kamsi Muoka Unwanaabasi Okon Ufot Chinyere Adanna Opara Usoro Source Type: research