Early predictors of remission in children and adolescents with new-onset epilepsy: a prospective study

It is well established that despite the availability of numerous novel antiseizure medications (ASMs), one third of children with new-onset seizures will not achieve seizure remission [1 –3]. These children endure the physical, psychological and social consequences of intractable seizures and face an elevated risk of death [4,5]. Despite its clinical importance, the early prediction of treatment outcome remains a major challenge [6], with only a limited number of large, community- based, long-term studies evaluating early predictors of medical refractoriness in childhood epilepsy [7–9].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research