Discordantly high Apo B with LDL-C or Non-HDL-C in Relation to Presence and Burden of Cerebral Atherosclerotic Plaques

Atherosclerotic cerebrovascular disease is a major public health issue and the second leading cause of morbidity and mortality in developing countries. 1 Elevated blood lipids, including low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (Non-HDL-C), were well-established risk factors for the development of atherosclerosis. 2 Multiple studies had demonstrated that apolipoprotein B (Apo B), a major structural protein of most lipoproteins and a measure of the atherogenic lipoprotein particle numbers, was a better predictive value for atherosclerotic diseases than LDL-C or Non-HDL-C.

Source: Journal of Clinical Lipidology - June 2, 2023 Category: Lipidology Authors: Chao Li, Yanli Zhang, Lerong Mei, Aoming Jin, Xueli Cai, Yuesong Pan, Jing Jing, Suying Wang, Xia Meng, Shan Li, Mengxing Wang, Tiemin Wei, Yongjun Wang, Rui Chen, Yu Tian Tags: Original Research Source Type: research