Comparison of two doses of leucovorin in severe low-dose methotrexate toxicity – a randomized controlled trial

Leucovorin (folinic acid) is a commonly used antidote for severe toxicity with low-dose methotrexate, but its optimum dose is unclear, varying from 15 to 25 mg every 6-h.

Source: Arthritis Research and Therapy - May 19, 2023 Category: Rheumatology Authors: Mudit Bhargava, Chirag Rajkumar Kopp, Shankar Naidu, Deba Prasad Dhibar, Atul Saroch, Alka Khadwal, Tarun Narang, Siddharth Jain, Aastha Khullar, Bidya Leishangthem, Aman Sharma, Susheel Kumar, Shefali Sharma, Sanjay Jain and Varun Dhir Tags: Research Source Type: research