Osteoarthritis genetic risk acting on the galactosyltransferase gene COLGALT2 has opposing functional effects in articulating joint tissues

Investigation of cartilage and chondrocytes has revealed that the osteoarthritis risk marked by the independent DNA variants rs11583641 and rs1046934 mediate their effects by decreasing the methylation status...

Source: Arthritis Research and Therapy - May 19, 2023 Category: Rheumatology Authors: Yulia S. Kehayova, J. Mark Wilkinson, Sarah J. Rice and John Loughlin Tags: Research Source Type: research