Cervical spinal cord stimulation for sleep-disordered breathing in multiple system atrophy

Multiple system atrophy (MSA) is a progressive, debilitating, and fatal neurodegenerative disease with motor and non-motor symptoms. Sleep-disordered breathing (SDB), commonly manifested as obstructive sleep apnea, is frequently observed among MSA patients and is a potential predictor of sudden death [1]. MSA patients present with stridor or snoring, resulting from the dysfunction of brainstem respiratory-associated motor neurons and weakness of the pharynx and larynx muscles, leading to an obstructive breathing pattern [2].

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 17, 2023 Category: Neurology Authors: Xue Zhu, Sijia Huang, Ning Li, Haiyan Zhou, Ningdi Luo, Fangzheng Chen, Yichi Zhang, Qianyi Yin, Zhengyu Lin, Peng Huang, Linbin Wang, Yuyan Tan, Dianyou Li, Jun Liu Source Type: research