Congenital Thrombotic Thrombocytopenic Purpura Masquerading As Vitamin B12 Deficiency

Congenital thrombotic thrombocytopenic purpura (CTTP), also called Upshaw-Schulman syndrome (USS), is a rare autosomal recessive disorder resulting from the deficiency of the ADAMTS13. CTTP is characterized by the formation of platelet-rich thrombi in small vessels of multiple organs, resulting in thrombocytopenia and microangiopathic hemolytic anemia, eventually leading to organ failure.

Source: Transfusion and Apheresis Science - May 15, 2023 Category: Hematology Authors: Deedar Nanjiani, Sohail Kumar, Nitik Sharma, Sundus Nasim, Dua Azim, Oam Parkash Source Type: research