1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B

CONCLUSION: 1,25(OH)2D3 could inhibit the development of oxidative stress and apoptosis in HaCaTs triggered by UVB. This inhibition might be achieved through the suppression of mitochondria-modulated apoptosis and autophagy. Vitamin D may be a potential UVB protective component.PMID:37130063 | DOI:10.1080/15569527.2023.2208676

Source: Cutaneous and Ocular Toxicology - May 2, 2023 Category: Toxicology Authors: Pingwei Wang Dongge Liu Jiajing Cui Shuqi Yan Yujun Liang Qianqian Chen Yanping Liu Shuping Ren Peng Chen Source Type: research