Differential effect of histone H3.3 depletion on retroviral repression in embryonic stem cells

Integration of retroviruses into the host genome can impair the genomic and epigenomic integrity of the cell. As a defense mechanism, epigenetic modifications on the proviral DNA repress retroviral sequences i...

Source: Clinical Epigenetics - May 11, 2023 Category: Research Authors: Ayellet Tal, Jose David Aguilera, Igor Bren, Carmit Strauss and Sharon Schlesinger Tags: Research Source Type: research