Cuproptosis-related gene CDKN2A as a molecular target for IPF diagnosis and therapeutics

ConclusionThese findings indicate that CDKN2A mediates the resistance of fibrosis-promoting M2 macrophages to cuproptosis and promotes pulmonary fibrosis in mice. Our work provides fresh insights into CRGs in IPF with potential value for research in the pathogenesis, diagnosis,  and a new therapy strategy for IPF.
Source: Inflammation Research - Category: Research Source Type: research