Enzalutamide Reduces Oxycodone Exposure in Men with Prostate Cancer

ConclusionCo-administration of enzalutamide significantly reduced exposure to oxycodone and its active metabolite oxymorphone in men with prostate cancer. This should be taken into account when prescribing enzalutamide combined with oxycodone.
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research