Enzalutamide Reduces Oxycodone Exposure in Men with Prostate Cancer

CONCLUSION: Co-administration of enzalutamide significantly reduced exposure to oxycodone and its active metabolite oxymorphone in men with prostate cancer. This should be taken into account when prescribing enzalutamide combined with oxycodone.PMID:37162620 | DOI:10.1007/s40262-023-01255-1

Source: Clinical Prostate Cancer - May 10, 2023 Category: Cancer & Oncology Authors: S E H Detert Oude Weme L M G Hulskotte W L Vervenne A L T Imholz R G H M Cremers K Taxis A K L Reyners I R F van Berlo-van de Laar F G A Jansman G E Benoist Source Type: research