Recommendations for risk stratification of periocular squamous cell carcinoma

Periocular squamous cell carcinoma (SCC) is a common cutaneous malignancy with generally favorable outcomes; however, the periocular region is intrinsically a high-risk location, and there exists a subset of lesions with a propensity for poor outcomes. Orbital invasion, intracranial perineural spread, nodal and distant metastasis are feared complications. There are several staging systems for eyelid carcinoma and cutaneous SCC, but the definition of high-risk lesions remains heterogeneous. It is unclear exactly which lesions can be safely deescalated, and which require nodal evaluation and adjuvant multimodal therapy.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Review article Source Type: research