Pharmacokinetics of N,N-dimethyltryptamine in Humans

ConclusionThis is the first study to determine, in detail, the full pharmacokinetics profile of DMT following a slow IV infusion in humans, confirming rapid attainment of peak plasma concentrations followed by rapid clearance. These findings provide evidence which supports the development of novel DMT infusion regimens for the treatment of MDD.Clinical Trial RegistrationRegistered on ClinicalTrials.gov (NCT04673383).
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research