Prevalence, causes and impact of TP53-loss phenocopying events in human tumors
TP53 is a master tumor suppressor gene, mutated in approximately half of all human cancers. Given the many regulatory roles of the corresponding p53 protein, it is possible to infer loss of p53 activity – which m...
Source: BMC Biology - Category: Biology Authors: Bruno Fito-Lopez, Marina Salvadores, Miguel-Martin Alvarez and Fran Supek Tags: Research article Source Type: research