Placental mesenchymal stem cells boost M2 alveolar over M1 bone marrow macrophages via IL-1{beta} in Klebsiella-mediated acute respiratory distress syndrome

Conclusions
Human PMSC treatment preferentially rescued resident M2 AMs over recruited M1 BMMs with overall M2 polarisation to improve KP-related ARDS survival.

Source: Thorax - April 13, 2023 Category: Respiratory Medicine Authors: Wang, L.-T., Yen, B. L., Wang, H.-H., Chao, Y.-Y., Lee, W., Huang, L.-Y., Chiu, S.-K., Siu, L. K., Liu, K.-J., Sytwu, H.-K., Yen, M.-L. Tags: Open access, Thorax Respiratory infection Source Type: research