Age-related effects of fenofibrate on the hepatic expression of sirtuin 1, sirtuin 3, and lipid metabolism-related genes

CONCLUSIONS: Treatment with fenofibrate at low or high doses may downregulate the expression of Sirt1 and Sirt3 proteins in the rat liver. The dosage of FN affects molecular changes, and aging alters the response to 0.5% FN.PMID:37023116 | DOI:10.18388/abp.2020_6538
Source: Acta Biochim Pol - Category: Biochemistry Authors: Source Type: research