Remdesivir-induced conduction abnormalities: A molecular model-based explanation

Conclusion: The proposed mechanism of exogenous cardiac A1 receptor activation from bioaccumulation of GS-441524 as a cause of observed cardiac conduction abnormalities with the use of remdesivir in COVID-19 is viable. Further studies are needed to assess causality.PMID:36942295 | PMC:PMC9990623 | DOI:10.3389/jpps.2023.11208
Source: Journal of Pharmacy and Pharmaceutical Sciences - Category: Drugs & Pharmacology Authors: Source Type: research