Single ‐ and Multiple‐dose Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1128, a Novel Peroxisome Proliferator‐activated Receptor δ Modulator, in Healthy Participants

In conclusion, single and multiple intravenous doses of ASP1128 were generally well tolerated, with dose-dependent pharmacokinetics and target gene engagement in healthy participants.

Source: Clinical Pharmacology in Drug Development - March 27, 2023 Category: Drugs & Pharmacology Authors: Yuta Taniuchi, J. W. Olivier Till, Tomasz Wojtkowski, Junko Toyoshima, Akira Koibuchi, Briana Sargent, David Han Tags: Original Article Source Type: research