A Tunable Calcium Phosphate Coating to Drive in vivo Osseointegration of Composite Engineered Tissues

This study also demonstrated that the use of SBF-based HA coatings can promote higher levels of osteogenesis in vivo. Finally, when incorporated as the endplate region of a larger tissue-engineered intervertebral disc replacement, HA coating did not induce mineralization in or promote cell migration out of neighboring biomaterials. Overall, these results verified tunable biomimetic HA coatings as a promising biomaterial modification to promote discrete regions of mineralization within composite engineered tissues.Cells Tissues Organs
Source: Cells Tissues Organs - Category: Cytology Source Type: research