Plasminogen activator inhibitor‐1 regulates tumor initiating cell properties in head and neck cancers

Conclusion
The inhibition of PAI‐1 by PAI‐039 or siRNA could suppress HNC‐TICs within HNC cell lines through the down‐regulation of Sox2. This article is protected by copyright. All rights reserved.

Source: Head and Neck - May 1, 2015 Category: ENT & OMF Authors: Yueh‐Chun Lee, Cheng‐Chia Yu, Chih Lan, Che‐Hsin Lee, Hsueh‐Te Lee, Yu‐Liang Kuo, Po‐Hui Wang, Wen‐Wei Chang Tags: Original Article Source Type: research