4-octyl itaconate improves the viability of D66H cells by regulating the KEAP1-NRF2-GCLC/HO-1 pathway

In conclusion, OI could improve the viability of HaCaT and D66H cells via regulating the KEAP1-NRF2-GCLC/HO-1 pathway, which provided a wide spectrum of potential targets for effective therapeutic treatments of Vohwinkel syndrome in the clinic.PMID:36916028 | DOI:10.1111/jcmm.17708

Source: Molecular Medicine - March 14, 2023 Category: Molecular Biology Authors: Yanrui Chen Zhenying Wang Yali Song Nan Chen Jing Guo Wenmin Liu Keying Guo Xia Ling Li Zhang Source Type: research