Update on Allergic Fungal Rhinosinusitis

Allergic fungal rhinosinusitis (AFRS) is a unique clinical entity that falls under the broader umbrella of chronic rhinosinusitis with nasal polyps (CRSwNP) with type 2 inflammation. It is characterized by nasal polyposis, production of characteristic thick eosinophilic mucin, and expansile change of involved sinus cavities.The diagnosis is classically made using the Bent and Kuhn criteria. However, recent studies have demonstrated lack of specificity of some major criteria. The need to fulfil all five criteria before diagnosing AFRS mitigates this partially, but renders the criteria cumbersome to use, and highlights the need to develop more specific criteria.

Source: Annals of Allergy, Asthma and Immunology - February 25, 2023 Category: Allergy & Immunology Authors: Andy J. Chua, Ali Jafar, Amber U. Luong Tags: CME Reviews Source Type: research