Excessive iodine induces thyroid follicular epithelial cells apoptosis by activating HIF-1 α-mediated hypoxia pathway in Hashimoto thyroiditis

CONCLUSION: Our study confirmed that excessive iodine adsorption activates the HIF-1α-mediated hypoxia pathway to promote apoptosis of TFCs, which may be an important risk factor contributing to HT development.PMID:36807042 | DOI:10.1007/s11033-023-08273-z
Source: Mol Biol Cell - Category: Molecular Biology Authors: Source Type: research