Continuous positive airway pressure as an accurate marker for non-24-hour sleep-wake rhythm disorder

We report the case of a 46-year-old man with autism spectrum disorder (ASD) and agoraphobia who had been referred for a suspicion of obstructive sleep apnea syndrome (OSAS). Polysomnography and arterial blood gas confirmed moderate OSAS associated with hypoventilation. Continuous positive airway pressure (CPAP) was started on fixed mode with excellent results. At follow-up, his CPAP report data revealed an irregular sleep-wake rhythm with a progressive offset of sleep schedule and wake time delayed from 1 h from day to day. Melatonin (or agonist) is efficacious and safe for long-term treatment in ASD and circadian rhythm sleep-wake disorder (CRSWD) with light therapy and wakefulness promoting medication. This case underlines the importance to sensitise psychiatrists to sleep and CRSWD, and also that CPAP data offer a possible objective alternative to sleep diary.PMID:36799093 | DOI:10.1111/jsr.13859

Source: Journal of Sleep Research - February 17, 2023 Category: Sleep Medicine Authors: Balthazar Bazin Pierre A Geoffroy H élène Benzaquen Julia Maruani Alix Romier Michel Lejoyeux Marie-Pia D'ortho Justine Frija-Masson Source Type: research