Platypnoea –orthodeoxia syndrome affects nocturnal oxygen desaturation: A case report

We herein describe a patient with severe sleep apnoea who was diagnosed with platypnoea –orthodeoxia syndrome (POS) after identification of unexplained hypoxia. The changes in SpO2 before and after surgery were characteristic of POS. AbstractA woman in her late 20s who had received an implantable cardioverter defibrillator in childhood for ventricular arrhythmia was diagnosed with severe obstructive sleep apnoea (apnoea –hypopnoea index, 77.1/h), and she began continuous positive airway pressure treatment. Before initiating this treatment, she had moderate hypoxaemia of unknown cause. She was admitted for adjustment of the position of her implantable cardioverter defibrillator, which had caused purple discolorati on and ulceration of the overlying skin. On admission, she had dyspnoea and her arterial oxygen saturation by pulse oximetry significantly decreased while sitting. This led to detection of a patent foramen ovale and a right-to-left shunt while sitting. We diagnosed platypnoea–orthodeoxia syndrome with an atrial septal defect. Atrial septal defects should be suspected in hypoxic patients with obstructive sleep apnoea.

Source: Respirology Case Reports - February 17, 2023 Category: Respiratory Medicine Authors: Mamiko Hoshi, Yutaka Kozu, Michio Kawamura, Naho Furusho, Ryosuke Ozoe, Yusuke Jinno, Kenichi Sugaya, Hisato Hiranuma, Kazuo Chin, Yasuhiro Gon Tags: CASE REPORT Source Type: research