Standardized airway wall thickness Pi10 from routine CT scans of COPD patients as imaging biomarker for disease severity, lung function decline, and mortality

CONCLUSION: In summary, Pi10 was found to be predictive for the course of the disease in COPD, in particular mortality. The fact that Pi10 was lower in patients with severe COPD receiving triple therapy might hint toward additional effects of this functional therapy on airway remodeling.REGISTRATION: ClinicalTrials.gov, Identifier: NCT01245933.PMID:36718763 | DOI:10.1177/17534666221148663

Source: Respiratory Care - January 31, 2023 Category: Respiratory Medicine Authors: Kathrin Kahnert Rudolf A J örres Hans-Ulrich Kauczor Peter Alter Franziska C Trudzinski Felix Herth Bertram Jobst Oliver Weinheimer Sebastian Nauck Pontus Mertsch Diego Kauffmann-Guerrero J ürgen Behr Robert Bals Henrik Watz Klaus F Rabe Tobias Welte Cl Source Type: research