Inhibition of RPTP β/ζ reduces chronic ethanol intake in adolescent mice and modulates ethanol effects on hippocampal neurogenesis and glial responses in a sex-dependent manner - Galán-Llario M, Rodríguez-Zapata M, Fontán-Baselga T, Gramage E, Vicente-Rodriguez M, Zapico JM, de Pascual-Teresa B, Lasek AW, Herradó n G.

Pleiotrophin (PTN) is a cytokine that modulates ethanol drinking and reward and regulates glial responses in different contexts. PTN is an inhibitor of Receptor Protein Tyrosine Phosphatase (RPTP) β/ζ. Inhibition of RPTPβ/ζ reduces binge-like drinking ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news