Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression

ConclusionThese results indicate that FXR-induced decrease in SESN2 expression and activation of the mTORC1 pathway could control autophagy and be explored as potential therapeutic targets for enterohepatic and metabolic disorders.This article is protected by copyright. All rights reserved

Source: Molecular Nutrition and Food Research - January 31, 2023 Category: Food Science Authors: GuoYan Wang, Lei Chen, SenLin Qin, HuiJun Geng, Chao Xia, YiNing Zheng, XinJian Lei, Jun Zhang, ShengRu Wu, JunHu Yao, Lu Deng Tags: Research Article Source Type: research