Prostatic carcinoma in a dog: a new approach by using the Gleason system

We describe the pathological features of prostatic carcinoma in a dog using the Gleason system where the related score was estimated as 7 (3 + 4). Perineural invasion was also noted, and the neoplastic cells showed no reaction with PSA antibody but were positive for Ki-67 and CK-7 and IHC staining. The expression of Ki-67-SI was 3.28 %. Traditional canine prostate cancer classification could not cover the obscured characteristics of our case; therefore, a more descriptive histological pattern system using the Gleason grading is recommended.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research