Risk assessment for colorectal cancer via polygenic risk score and lifestyle  exposure: a large-scale association study of East Asian and European populations

ConclusionsIn summary, we systemically constructed an EAS-EUR PRS to effectively stratify colorectal cancer risk, which highlighted its clinical implication among diverse ancestries. Importantly, these findings also supported that a healthy lifestyle could reduce the genetic impact on incident colorectal cancer.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research