RAGE inhibition alleviates lipopolysaccharides-induced lung injury via directly suppressing autophagic apoptosis of type II alveolar epithelial cells

CONCLUSION: RAGE plays an essential role in the pathogenesis of ATII cells injury. Our results suggested that RAGE inhibition alleviated LPS-induced lung injury by directly suppressing autophagic apoptosis of alveolar epithelial cells.PMID:36691012 | DOI:10.1186/s12931-023-02332-6

Source: Respiratory Care - January 23, 2023 Category: Respiratory Medicine Authors: Xi Xiong Jiaying Dou Jingyi Shi Yuqian Ren Chunxia Wang Yucai Zhang Yun Cui Source Type: research