18F-FP-CIT dopamine transporter PET findings in the striatum and retina of type 1 diabetic rats

ConclusionsDA neuron loss in the  striatum and retina of T1DM rat model can be non-invasively detected with PET imaging using18F-FP-CIT targeting DAT.18F-FP-CIT PET imaging may be a useful tool used in clinic for DR and diabetic brain injury diagnosis in future. The expression level of DAT in striatum and retina may act as a new biomarker for DR and diabetic brain injury diagnosis.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research