APOE effects on regional tau in preclinical Alzheimer ’s disease

APOE variants are strongly associated with abnormal amyloid aggregation and additional direct effects of APOE on tau aggregation are reported in animal and human cell models. The degree to which these effects are...

Source: Molecular Neurodegeneration - January 4, 2023 Category: Neurology Authors: Christina B. Young, Emily Johns, Gabriel Kennedy, Michael E. Belloy, Philip S. Insel, Michael D. Greicius, Reisa A. Sperling, Keith A. Johnson, Kathleen L. Poston and Elizabeth C. Mormino Tags: Research article Source Type: research