Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review

CONCLUSIONS: Our review shows that the use of ASMs that act throughout a gabaergic mechanism are inadequate in controlling seizures secondary to neonatal stroke in full-term newborns. Very effective seems to be lidocaine and levetiracetam with an apparent safer profile in short and long term. Bumetanide shows promising results, but they need to be confirmed by phase 3 studies.PMID:36533757 | DOI:10.23750/abm.v93i6.13440
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Source Type: research