Busting the myth of methotrexate chronic hepatotoxicity

Nature Reviews Rheumatology, Published online: 23 December 2022; doi:10.1038/s41584-022-00883-4Methotrexate is commonly used in the treatment of inflammatory rheumatic diseases. In this Review, the authors discuss the potential hepatotoxicity of methotrexate, with particular consideration of the role of chronic liver disease, and suggest screening and monitoring strategies for patients receiving methotrexate.

Source: Nature Reviews Rheumatology - December 23, 2022 Category: Rheumatology Authors: Vincent Di Martino Delphine Weil Verhoeven Frank Verhoeven Fran çois Aubin J érome Avouac Lucine Vuitton Fr édéric Lioté Thierry Th évenot Daniel Wendling Source Type: research