WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma

ConclusionsThese data implicate WNT5A-ROR2 in VEGF secretion, vascularity, adverse outcomes and bevacizumab sensitivity of BRAFMut melanomas, suggesting that this axis has potential therapeutic relevance.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research