Efficacy and safety of rituximab in myelin oligodendrocyte glycoprotein antibody-associated disorders compared with neuromyelitis optica spectrum disorder: a systematic review and meta-analysis
Conclusions
RTX showed effective in MOGAD, although to a lesser extent than in AQP4-IgG+NMOSD, while the safety profile warrants some caution in its prescription. Randomised-controlled trials are needed to confirm these findings and provide robust evidence to improve treatment strategies in patients with MOGAD.
PROSPERO registration number
CRD42020175439.
Source: Journal of Neurology, Neurosurgery and Psychiatry - Category: Neurosurgery Authors: Spagni, G., Sun, B., Monte, G., Sechi, E., Iorio, R., Evoli, A., Damato, V. Tags: Neuro-inflammation Source Type: research