Class of hemorrhagic shock is associated with progressive diastolic coronary flow reversal and diminished left ventricular function

Conclusion: With progressive classes of hemorrhagic shock left ventricular function progressively decreased, and the coronary arteries spent a greater proportion of diastole in retrograde flow, with progressively more negative total coronary flow. Preload recruitable stroke work, a load-independent measure of inotropy, also worsened in severe hemorrhagic shock, indicating the mechanism extends beyond the drop in preload and afterload alone.
Source: Frontiers in Physiology - Category: Physiology Source Type: research